Oncolytic Vaccinia Virus OVV-01

**Semantic type:** Pharmacologic Substance|Virus

**Definition:** An oncolytic vaccinia virus (VV), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration of the oncolytic vaccinia virus OVV-01, the virus preferentially targets and infects tumor cells, thereby causing oncolysis. In turn, the lysed tumor cells release various tumor-associated antigens (TAAs), which induce an immune response against the tumor cells. This further kills tumor cells.

**Synonyms:** - C045 - OVV 01 - OVV-01 - OVV01 - Oncolytic Virus OVV-01