PRC2 Loss of Function Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of a gene encoding a protein that is a component of polycomb repressive complex 2 (PRC2) and results in a decrease or loss of PRC2 histone methyltransferase activity.

**Synonyms:** - Inactivating PRC2 Gene Mutation - Inactivating PRC2 Mutation - PRC2 Inactivating Gene Mutation - PRC2 Inactivating Mutation - PRC2 Loss - PRC2 Loss of Function Mutation - Polycomb Repressive Complex 2 Loss of Function Gene Mutation - Polycomb Repressive Complex 2 Loss of Function Mutation