Clostridial Collagenase Ointment

**Semantic type:** Pharmacologic Substance

**Definition:** A topical ointment formulation containing the enzyme collagenase derived from the fermentation by Clostridium histolyticum in a white petrolatum base, with enzymatic debriding activity. Upon topical application of clostridial collagenase ointment, the collagenase digests collagen in necrotic tissue resulting in enzymatic debridement which may promote wound healing.

**Synonyms:** - Collagenase - Collagenase Ointment - Collagenase Topical Ointment - Santyl