Mothers Against Decapentaplegic Homolog 3

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Mothers against decapentaplegic homolog 3 (425 aa, ~48 kDa) is encoded by the human SMAD3 gene. This protein plays a role in the modulation of transforming growth factor (TGF)-beta-mediated signaling and gene expression.

**Synonyms:** - JV15-2 - MAD Homolog 3 - MADH3 - Mad Homolog JV15-2 - Mad Protein Homolog 3 - Mad3 - Mothers Against DPP Homolog 3 - Mothers Against Decapentaplegic Homolog 3 Protein - Mothers Against Decapentaplegic, Drosophila, Homolog of, 3 - SMA- and MAD-Related Protein 3 - SMAD 3 - SMAD Family Member 3 - SMAD3 Protein - Smad3 - hMAD-3 - hSMAD3