POLEm Endometrial Endometrioid Adenocarcinoma

**Semantic type:** Neoplastic Process

**Definition:** An endometrial endometrioid adenocarcinoma characterized by mutations in the exonuclease domain of the DNA polymerase epsilon (POLE) gene that result in an ultra-mutated tumor phenotype.

**Synonyms:** - POLE-Ultra-Mutated Endometrial Endometrioid Adenocarcinoma - POLE-Ultra-Mutated Endometrial Endometrioid Carcinoma - POLE-Ultramutated Endometrial Endometrioid Adenocarcinoma - POLE-Ultramutated Endometrial Endometrioid Carcinoma - POLEm Endometrial Endometrioid Carcinoma