Hypermutated/MMRd Endometrial Endometrioid Adenocarcinoma

**Semantic type:** Neoplastic Process

**Definition:** An endometrial endometrioid adenocarcinoma characterized by mismatch repair (MMR) deficiency caused by inactivating methylation or less frequently mutation of an MMR gene (MLH1, PMS2, MSH2, or MSH6).

**Synonyms:** - Hypermutated/MMRd Endometrial Endometrioid Carcinoma - Mismatch Repair-Deficient Endometrial Endometrioid Adenocarcinoma - Mismatch Repair-Deficient Endometrial Endometrioid Carcinoma