Autologous Anti-gp100:154-162 TCR Tumor Infiltrating Lymphocytes

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of human tumor infiltrating lymphocytes (TILs) isolated from a melanoma patient and engineered to encode a T-cell receptor (TCR) specific for the amino acid 154 through 162 of the melanoma antigen glycoprotein 100 (gp100), with potential immunomodulating and antineoplastic activities. Upon intravenous administration, the autologous anti-gp100:154-162 TCR TILs may recognize and halt the growth of gp100-expressing melanoma cells.

**Synonyms:** - Autologous Anti-gp 100:154-162 TCR TILs - Autologous Anti-gp100:154-162 TCR Gene Engineered TILs - Autologous Anti-gp100:154-162 TCR Gene-engineered Tumor Infiltrating Lymphocytes - Autologous Anti-gp100:154-162 TCR TILs - Autologous Anti-gp100:154-162 TCR-engineered TILs