Clostridium difficile Infection

**Semantic type:** Disease or Syndrome

**Definition:** A bacterial infection caused by Clostridium difficile (Clostridioides difficile), which is a spore-forming, toxin-producing Gram-positive anaerobic bacillus that is transmitted by the fecal-oral route. Infection may cause symptoms ranging from diarrhea to life-threatening inflammation of the colon, and risk factors include use of antibiotic medication, advanced age, and hospital or long-term care facility admission.

**Synonyms:** - C. diff Infection - C. diff Infection - Clostridioides difficile (c. diff) - Clostridioides difficile Infection - Clostridioides difficile Infection