Autologous Anti-MART-1 F5 TCR Tumor Infiltrating Lymphocytes

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of human tumor infiltrating lymphocytes (TILs) isolated from a melanoma patient and engineered to encode a T-cell receptor (TCR) specific for an epitope of MART-1 (F5 TCR), with potential immunomodulating and antineoplastic activities. Upon administration, the autologous anti-MART-1 F5 TCR TILs may recognize and halt the growth of MART-1-expressing melanoma cells.

**Synonyms:** - Autologous Anti-MART-1 F5 TCR Gene Engineered TILs - Autologous Anti-MART-1 F5 TCR Gene-engineered Tumor Infiltrating Lymphocytes - Autologous Anti-MART-1 F5 TCR TILs - Autologous Anti-MART-1 F5 TCR-engineered TILs