Somatic Variation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** Any mutation with an origin in cells that are not destined to become gametes. As a consequence, such mutations are not transmitted to progeny, though they will be transmitted during any mitosis within the individual. Somatic mutations may contribute to a broad variety of pathologies including cancer.

**Synonyms:** - SOMATIC VARIATION - Somatic Mutation - Somatic Mutation - Somatic Mutation Abnormality - Somatic Variant - somatic mutation