BICC1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human BICC1 wild-type allele is located in the vicinity of 10q21.1 and is approximately 319 kb in length. This allele, which encodes protein bicaudal C homolog 1, plays a role in RNA binding. Mutation of the gene is associated with susceptibility to cystic renal dysplasia and a translocation that fuses this gene with the FGFR2 gene is associated with cholangiocarcinoma.

**Synonyms:** - BICC - BicC Family RNA Binding Protein 1 wt Allele - Bicaudal C Homolog 1 (Drosophila) Gene - Bicaudal C Homolog 1 Gene - Bicaudal C, Drosophila, Homolog, 1 Gene - CYSRD