Yttrium Y-90 Ibritumomab Tiuxetan

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A radioimmunotherapeutic agent consisting of a murine monoclonal anti-CD20 antibody (ibritumomab) linked by the chelator tiuxetan to the radioisotope yttrium-90 (Y 90). Yttrium Y 90 ibritumomab tiuxetan binds to and specifically delivers beta radiation to CD20-expressing tumor cells, thereby minimizing the systemic effects of radiation.

**Synonyms:** - IDEC-Y2B8 - IDEC-Y2B8 monoclonal antibody - Y 90 Ibritumomab Tiuxetan - Y 90 Zevalin - Y 90 ibritumomab tiuxetan - YTTRIUM Y-90 IBRITUMOMAB TIUXETAN - Yttrium Y 90 Ibritumomab Tiuxetan - yttrium Y90 ibritumomab tiuxetan