Functional Microbial-induced Antibody Measurement

**Semantic type:** Laboratory Procedure

**Definition:** The determination of the functional binding of microbial-induced antibody in a biospecimen. A functional microbial-induced antibody is defined as antibodies that have agonist or antagonist effects on pathogens or their toxins in the presence of other effector molecules or cells. For example, the effects of functional antibodies can include neutralization, phagocytosis, antibody-dependent cellular cytotoxicity, and complement-mediated lysis. The production of this antibody may be triggered by naturally occurring infection and/or vaccination using a whole microbe or component(s) of a microbe.

**Synonyms:** - Functional Microbial-induced Antibody - Functional Microbial-induced Antibody - MBFAB