RPS6KA3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RPS6KA3 wild-type allele is located in the vicinity of Xp22.12 and is approximately 118 kb in length. This allele, which encodes ribosomal protein S6 kinase alpha-3 protein, is involved in the modulation of transcription factor phosphorylation and activation. Mutation of the gene is associated with both Coffin-Lowry syndrome and X-linked intellectual developmental disorder type 19.

**Synonyms:** - CLS - HU-3 - ISPK-1 - ISPK1 - MAPKAPK1B - MRX19 - RSK - RSK2 - Ribosomal Protein S6 Kinase A3 wt Allele - Ribosomal Protein S6 Kinase, 90-kD, 3 Gene - Ribosomal Protein S6 Kinase, 90kD, Polypeptide 3 Gene - Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 Gene - Ribosomal S6 Kinase 2 Gene - S6K-Alpha-3 - S6K-alpha3 - XLID19 - p90-RSK2 - pp90RSK2