TSHB wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TSHB wild-type allele is located in the vicinity of 1p13.2 and is approximately 6 kb in length. This allele, which encodes thyrotropin subunit beta protein, plays a role in thyroid development and thyroid hormone production. Mutation of the gene is associated with congenital nongoitrous hypothyroidism type 4, congenital central and secondary hypothyroidism and Hashimoto's thyroiditis.

**Synonyms:** - TSH-B - TSH-BETA - Thyroid Stimulating Hormone Beta Gene - Thyroid Stimulating Hormone Subunit Beta wt Allele - Thyroid Stimulating Hormone, Beta Chain Gene - Thyrotropin, Beta Chain Gene