HUWE1 Gene

**Semantic type:** Gene or Genome

**Definition:** This gene is involved in the ubiquitination and subsequent proteasomal degradation of induced myeloid leukemia cell differentiation protein Mcl-1, cellular tumor antigen p53, core histone proteins and DNA polymerase beta.

**Synonyms:** - HECT, UBA and WWE Domain Containing E3 Ubiquitin Protein Ligase 1 Gene - HUWE1 - HUWE1