MASP2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MASP2 wild-type allele is located in the vicinity of 1p36.22 and is approximately 21 kb in length. This allele, which encodes mannan-binding lectin serine protease 2 protein, is involved in antibody-independent activation of complement. Loss of function mutations in the gene are associated with defect in lectin complement activation pathway type 2 (MASP2 deficiency).

**Synonyms:** - MAP-2 - MAP19 - MASP-2 - MASP1P1 - MBL Associated Serine Protease 2 wt Allele - MBL-Associated Plasma Protein of 19 kD Gene - Mannan-Binding Lectin Serine Peptidase 1 Pseudogene 1 Gene - Mannan-Binding Lectin Serine Protease 1 Pseudogene 1 Gene - Mannose-Binding Lectin Associated Protein 19 Gene - Map19 - Small MBL-Associated Protein Gene - sMAP