Lipid Nanoparticle-encapsulated SARS-CoV-2 mRNA Vaccine PTX-COVID19-B

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A vaccine consisting of a lipid nanoparticle (LNP) encapsulating a messenger RNA (mRNA) encoding a full-length version of the spike (S) protein of SARS-CoV-2, with potential immunizing activity against SARS-CoV-2. Upon administration of the LNP-encapsulated SARS-CoV-2 mRNA vaccine PTX-COVID19-B, the lipid nanoparticle binds to the plasma membrane of cells and releases the mRNA into the cells. The mRNA is then translated by ribosomes to produce the SARS-CoV-2 S protein. This may activate both humoral and cellular immune responses which may result in protection against SARS-CoV-2 infection.

**Synonyms:** - LNP-encapsulated SARS-CoV-2 mRNA Vaccine PTX-COVID19-B - PTX-COVID19-B