Oncogene MET

**Semantic type:** Gene or Genome

**Definition:** The MET oncogene is derived from a chromosomal rearrangement involving the MET and TPR (translocated promoter region) loci and is a cloned gene for Hereditary Papillary Renal Carcinoma. The MET proto-oncogene encodes hepatocyte growth factor receptor, a disulfide-linked two subunit receptor protein tyrosine kinase. The human gene is located at 7q31.

**Synonyms:** - Activated Hepatocyte Growth Factor Receptor Gene - Hepatocyte Growth Factor Receptor Gene - MET - Oncogene HGFR