Suppression of Tumorigenicity 5 Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Suppression of tumorigenicity 5 protein (1137 aa, ~126 kDa) is encoded by the human DENND2B gene. This protein plays a role in the cytoskeletal organization, EGFR trafficking/recycling and activation of the MAPK1 pathway.

**Synonyms:** - DENN Domain-Containing Protein 2B - DENND2B - DENND2B Isoform 1 - HeLa Tumor Suppression 1 - HeLa Tumor Suppression 1 Protein - ST5 - Suppression of Tumorigenicity 5 - Suppression of Tumorigenicity 5 Protein Isoform 1 - Suppressor of Tumorigenicity 5 - p126