Oncolytic Vaccinia Virus PF-07263689

**Semantic type:** Pharmacologic Substance

**Definition:** An engineered oncolytic vaccinia virus (VV), with potential immunomodulating and antineoplastic activities. Upon administration of oncolytic VV PF-07263689, the virus preferentially targets and infects tumor cells, thereby causing oncolysis. In turn, the lysed tumor cells release various tumor-associated antigens (TAAs), which induce an immune response against the tumor cells. This further kills tumor cells.

**Synonyms:** - Oncolytic VV PF-07263689 - PF 07263689 - PF-07263689 - PF07263689