Oncogene DBL

**Semantic type:** Gene or Genome

**Definition:** Human oncogene DBL is a mutated form of the MCF.2 cell line derived transforming sequence (MCF2) gene, located at Xq27, which encodes 4 alternative variants of the proto-oncogene DBL protein. Activation of the DBL oncogene is generated by 5-prime recombination with chromosome 3pter-p21 and by 3-prime recombination with chromosome 16p13-q22.

**Synonyms:** - DBL - Diffuse B-Cell Lymphoma Oncogene - MCF.2 Cell Line Derived Transforming Sequence - MCF2 - MCF2 Gene - Oncogene MCF2 - Oncogene, DBL - Oncogene, MCF-2