TUBB4A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TUBB4A wild-type allele is located in the vicinity of 19p13.3 and is approximately 9 kb in length. This allele, which encodes tubulin beta-4A chain protein, plays a role in microtubule structure and function. Mutations in the gene are associated with hypomyelinating leukodystrophy-6 and autosomal dominant torsion dystonia-4.

**Synonyms:** - Class IVa Beta-Tubulin Gene - DYT4 - Dystonia 4, Torsion (Autosomal Dominant) Gene - TUBB4 - TUBB5 - Tubulin Beta 4A Class IVa wt Allele - Tubulin, Beta 4 Class IVa Gene - Tubulin, Beta 4 Gene - Tubulin, Beta, 5 Gene - Tubulin, Beta, Class IVa Gene - Tubulin, Beta-4A Gene - beta-5