Histidine-tRNA Ligase, Cytoplasmic

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Histidine-tRNA ligase, cytoplasmic (509 aa, ~57 kDa) is encoded by the human HARS1 gene. This protein plays a role in the ATP-dependent ligation of histidine to the 3'-end of tRNA.

**Synonyms:** - EC 6.1.1.21 - HARS1 - HisRS - HisRS - Histidine Translase - Histidine tRNA Ligase 1, Cytoplasmic - Histidine tRNA Ligase 1, Cytoplasmic - Histidine--tRNA Ligase, Cytoplasmic - Histidine-tRNA Synthetase, Cytoplasmic - Histidyl-tRNA Synthetase - Histidyl-tRNA Synthetase 1 - Histidyl-tRNA Synthetase 1 - JO-1 ANTIGEN - Jo-1 Antigen