Inactivating PIK3R1 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the PIK3R1 gene that either inhibits expression or results in the translation of an inactive phosphatidylinositol 3-kinase regulatory subunit alpha protein.

**Synonyms:** - Inactivating GRB1 Gene Mutation - Inactivating PIK3R1 Mutation - Inactivating Phosphoinositide-3-Kinase Regulatory Subunit 1 Gene Mutation - Inactivating p85-ALPHA Gene Mutation - Loss of Function PIK3R1 Gene Mutation - Loss of Function PIK3R1 Mutation - PIK3R1 Loss of Function Gene Mutation - PIK3R1 Loss of Function Mutation