Anti-KLK2 CAR-T Cells JNJ-75229414

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting human kallikrein-2 (hK2; KLK2) expressed on tumor cells, with potential immunostimulating and antineoplastic activities. Upon administration, anti-KLK2 CAR-T cells JNJ-75229414 target and bind to KLK2-expressing tumor cells, thereby inducing selective toxicity in KLK2-expressing tumor cells. KLK2 is overexpressed in certain tumors, including prostate adenocarcinoma.

**Synonyms:** - Anti-KLK2 CAR T Cells JNJ-75229414 - Anti-kallikrein-2 CAR T-cells JNJ-75229414 - JNJ 75229414 - JNJ-75229414 - JNJ75229414 - KLK2 CAR-T Cells JNJ-75229414