Soluble Receptor Tyrosine-Protein Kinase erbB-2

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Soluble receptor tyrosine-protein kinase erbB-2 is encoded by the human ERBB2 gene. This protein may be involved in binding to receptor tyrosine-protein kinase erbB-2, which leads to disruption of dimer formation, reduced receptor phosphorylation, and inhibition of cell growth.

**Synonyms:** - ERBB2 - ERBB2 ECD - ERBB2 Extracellular Domain - HER2 ECD - HER2 Extracellular Domain - Herstatin - Soluble ERBB2 - Soluble ErbB-2 - sERBB2 - sErbB-2