Non-Inferiority Trial

**Semantic type:** Research Activity

**Definition:** A type of controlled trial to demonstrate that the new treatment is not less effective than the active control by a specified amount. [After Non-Inferiority Clinical Trials to Establish Effectiveness. FDA Guidance for Industry. November 2016]

**Synonyms:** - NI Trial - Non-Inferiority Study - non-inferiority (NI) trial - non-inferiority trial