POLR1D wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human POLR1D wild-type allele is located in the vicinity of 13q12.2 and is approximately 123 kb in length. This allele, which encodes DNA-directed RNA polymerases I and III subunit RPAC2 protein, is involved in RNA polymerase I- and III-dependent transcription of rRNA and other small RNAs. Mutation of the gene is associated with Treacher Collins syndrome 2.

**Synonyms:** - AC19 - MGC9850 - POLR1C - Polymerase (RNA) I Polypeptide D, 16kDa Gene - Polymerase (RNA) I Subunit D Gene - Polymerase I, RNA, Subunit D Gene - RNA Polymerase A, 16-kD, Mouse, Homolog of Gene - RNA Polymerase I and III Subunit D wt Allele - RPA16 - RPA9 - RPAC2 - RPC16 - RPO1-3 - TCS2