MAPK Pathway Activating Gene Alteration Positive

**Semantic type:** Laboratory or Test Result

**Definition:** An indication that gene alterations that result in activation of the MAPK signaling pathway have been detected. Causative gene alterations include mutations resulting in the expression of BRAF p.V600E and gene fusions involving FGFR2 or FGFR3.

**Synonyms:** - MAP Kinase Pathway Activating Gene Alteration Positive - MAPK Pathway-Activating Genetic Abnormality - MAPK Pathway-Activation Positive