SARS-CoV-2 Protein Subunit Vaccine AKS-452

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** An engineered protein subunit vaccine composed of an Fc fusion protein of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike (S) protein receptor binding domain (RBD) antigen and human immunoglobulin G1 (IgG1) Fc, with potential immunizing activity against SARS-CoV-2. Upon administration of the SARS-CoV-2 protein subunit vaccine AKS-452, the S protein activates the immune system to create anti-SARS-CoV-2 S protein antibodies. The antibodies recognize and neutralize the S protein and kill SARS-CoV-2. This prevents SARS-CoV-2 infection. S protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus.

**Synonyms:** - AKS 452 - AKS-452 - AKS452 - COVID-19 Vaccine AKS-452 - Fc Fusion COVID-19 Subunit Vaccine AKS-452 - SARS-CoV-2 Vaccine AKS-452