CIT wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CIT wild-type allele is located in the vicinity of 12q24.23 and is approximately 192 kb in length. This allele, which encodes citron Rho-interacting kinase protein, is involved in the regulation of Rho family of GTPase activity, cytokinesis and serine/threonine kinase activity. Mutation of the gene is associated with primary, autosomal recessive microcephaly 17.

**Synonyms:** - CITK - CRIK - Citron (Rho-Interacting, Serine/Threonine Kinase 21) Gene - Citron Rho-Interacting Serine/Threonine Kinase wt Allele - KIAA0949 - MCPH17 - STK21