TPM3/NTRK1 Fusion Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein (641 aa, ~72 kDa) encoded by the TPM3/NTRK1 fusion gene. This protein is comprised of most of the tropomyosin alpha-3 chain protein fused to the C-terminus of the high affinity nerve growth factor receptor protein, including an intact tyrosine kinase domain.

**Synonyms:** - NTRK1/Tropomyosin Chimeric Protein - TPM3-NTRK1 Fusion Protein - TPM3::NTRK1 Fusion Protein - Tropomyosin Alpha-3 Chain/ High Affinity Nerve Growth Factor Receptor Fusion Protein