Bacillus Calmette-Guerin Unresponsive Disease

**Semantic type:** Finding

**Definition:** An indication that a neoplastic disease, usually non-muscle invasive bladder cancer (NMIBC), is unresponsive to bacillus Calmette-Guerin (BCG) induction therapy and that additional BCG therapy is unlikely to benefit the subject. Unresponsive subjects include those with recurrent disease within 12 months of the completion of adequate BCG therapy, recurrent high-grade disease within 6 months of the completion of adequate BCG therapy or high-grade disease at the first evaluation after a BCG induction course.

**Synonyms:** - BCG-Unresponsive - BCG-Unresponsive Disease - Bacillus Calmette-Guerin Unresponsive - Bacillus Calmette-Guérin Unresponsive - Bacillus Calmette-Guérin Unresponsive Disease