Hemoglobin Beta Homozygous Insufficient Genotype

**Semantic type:** Laboratory or Test Result

**Definition:** A genetic finding indicating that both copies of chromosome 16 each have a copy of the hemoglobin beta gene (HBB) with mutations that lead to hemoglobin subunit beta insufficiency (B+). This genotype is associated with beta thalassemia intermedia.

**Synonyms:** - (B+/B+) - B+/B+ - HBB Homozygous Insufficient Genotype - HBB Insufficient Genotype - beta-globin genotype (B+/B+)