TNIK wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TNIK wild-type allele is located within 3q26.2-q26.31 and is approximately 402 kb in length. This allele, which encodes TRAF2 and NCK-interacting protein kinase protein, is involved in serine/threonine phosphorylation and activation of the Wnt signaling pathway. Mutation of the gene is associated with intellectual developmental disorder 54.

**Synonyms:** - KIAA0551 - MRT54 - TRAF2 and NCK Interacting Kinase wt Allele