RAPGEF2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RAPGEF2 wild-type allele is located in the vicinity of 4q32.1 and is approximately 257 kb in length. This allele, which encodes Rap guanine nucleotide exchange factor 2 protein, plays a role in the activation of Rap and Ras family GTPases. A repeat expansion in the gene may be associated with familial adult myoclonic epilepsy 7.

**Synonyms:** - CNrasGEF - DKFZP586O1422 - KIAA0313 - NRAPGEP - PDZ Domain Containing Guanine Nucleotide Exchange Factor (GEF) 1 Gene - PDZ-GEF1 - PDZGEF1 - RA(Ras/Rap1A-Associating)-GEF Gene - RA-GEF - RA-GEF-1 - RAGEF - Rap GEP - Rap Guanine Nucleotide Exchange Factor (GEF) 2 Gene - Rap Guanine Nucleotide Exchange Factor 2 wt Allele - Rap-GEP - nRap GEP - nRap_GEP