Prednisolone Sodium Metasulfobenzoate

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A poorly adsorbed analog of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI)

**Synonyms:** - ATL-2502 - Corti-Clyss - PREDNISOLONE SODIUM METAZOATE - Predenema - Predfoam - Prednisolone Methylsulfobenzoate - Prednisolone Sodium 21-M-Sulfobenzoate - Prednisolone Sodium Metasulphobenzoate - Predocol - Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-, 21-(M-sulfobenzoate), Monosodium Salt