Allogeneic Virus-specific T-lymphocytes R-MVST

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of allogeneic T-lymphocytes generated from partially human leukocyte antigen (HLA)-matched healthy donors or from the original allogeneic hematopoietic stem cell transplantation (HSCT) donor, ex-vivo expanded, and specifically reactive to viruses that may include adenovirus (AdV), cytomegalovirus (CMV), Epstein-Barr virus (EBV) and human polyomavirus type I (BKV), with potential antiviral activity. Upon administration, the allogeneic virus-specific T-lymphocytes R-MVST may kill AdV, CMV, EBV and/or BKV-infected cells, and may prevent or reduce the severity of viral infections by these pathogens.

**Synonyms:** - R-MVST - R-MVST Cells - Rapidly-generated Virus-specific T-cells