Lenacapavir Sodium

**Semantic type:** Pharmacologic Substance

**Definition:** The sodium salt form of lenacapavir, an inhibitor of human immunodeficiency virus type 1 (HIV-1) capsid function, with activity against HIV. Upon administration, lenacapavir targets and binds to the interface between HIV capsid protein (p24) subunits in hexamers. This inhibits capsid function, including capsid-mediated nuclear uptake of preintegration complexes, virion production and proper capsid core formation, thereby inhibiting HIV-1 replication.

**Synonyms:** - LENACAPAVIR SODIUM - Sunlenca - Sunlenca