Central Nervous System CIC-Rearranged Sarcoma

**Semantic type:** Neoplastic Process

**Definition:** A rare, undifferentiated, high grade small round cell sarcoma that arises from the central nervous system. It is characterized by a recurrent translocation involving the CIC gene on chromosome 19 resulting in CIC gene fusion with different gene partners.

**Synonyms:** - CNS CIC-Rearranged Sarcoma