TPBG wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TPBG wild-type allele is located in the vicinity of 6q14.1 and is approximately 4 kb in length. This allele, which encodes trophoblast glycoprotein, plays a role in Wnt-signaling and cell adhesion. Overexpression of the gene is observed in a wide spectrum of neoplastic diseases, including colorectal, ovarian and gastric carcinomas.

**Synonyms:** - 5T4 - 5T4-AG - 5T4AG - M6P1 - Trophoblast Glycoprotein wt Allele - WAIF1