OPA1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human OPA1 wild-type allele is located in the vicinity of 3q29 and is approximately 105 kb in length. This allele, which encodes dynamin-like 120 kDa protein, mitochondrial, is involved in the regulation of fusion and fission of mitochondria. Mutations in this gene are associated with optic atrophy type 1, mitochondrial DNA depletion syndrome 14 and Behr syndrome.

**Synonyms:** - BERHS - FLJ12460 - KIAA0567 - MGM1 - MTDPS14 - NPG - NTG - OPA1 Mitochondrial Dynamin Like GTPase wt Allele - OPA1 Mitochondrial Dynamin-Like GTPase Gene - OPA1, Mitochondrial Dynamin Like GTPase Gene - Optic Atrophy 1 (Autosomal Dominant) Gene - largeG