Poly [ADP-Ribose] Polymerase Tankyrase-2

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Poly [ADP-ribose] polymerase tankyrase-2 (1166 aa, ~127 kDa) is encoded by the human TNKS2 gene. This protein is involved in poly-ADP-ribosylation of protein substrates and regulates telomere maintenance and protein ubiquitination and degradation.

**Synonyms:** - ADP-Ribosyltransferase Diphtheria Toxin-Like 6 - ARTD6 - EC 2.4.2.30 - Poly [ADP-Ribose] Polymerase 5B - Protein Poly-ADP-Ribosyltransferase Tankyrase-2 - TANK2 - TNKS-2 - TNKS2 - TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 - Tankyrase 2 - Tankyrase II - Tankyrase-2 - Tankyrase-Like Protein - Tankyrase-Related Protein