EGFR/HER1/HER2 Inhibitor PKI166

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A pyrrolo-pyrimidine epidermal growth factor receptor (EGFR) protein kinase inhibitor with anti-tumor activity. PKI-166 reversibly inhibits HER1 and HER2 tyrosine kinases, belong to the epidermal growth factor receptor family, thereby inhibiting tumor growth and metastasis.

**Synonyms:** - CGP 75166 - CGP 75166/PKI166 - CGP75166] - PKI-166 - PKI-166 - PKI166 - PKI166