SARS Coronavirus 2 BA.4

**Semantic type:** Virus

**Definition:** A variant lineage of SARS coronavirus 2 where the following variations in the spike glycoprotein sequence have been identified: deletions of the amino acids at positions 25/27 and 69/70 and amino acid substitutions T19I, L24S, G142D, V213G, G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H and N969K. This variant has two novel amino acid variations, a D61L substitution in the ORF6 protein and a L11F in the ORF7b protein.

**Synonyms:** - B.1.1.529.4 - BA.4 - Omicron - Omicron (BA.4) - SARS Coronavirus 2 Variant Lineage BA.4 - SARS-CoV-2 BA.4 - SARS2 BA.4