C187222Level 4
Nicotinic Acetylcholine Receptor
**Semantic type:** Amino Acid, Peptide, or Protein|Receptor
**Definition:** Heteropentameric transmembrane protein complexes that act as ligand-gated cation-specific channels in response to acetylcholine- and nicotine-binding. Nicotinic acetylcholine receptors are expressed in a wide varietly of cell and tissue types and are involved in neurotransmission, muscle contraction and inflammation.
**Synonyms:** - Nicotinic Receptor - nAChR
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