Anti-Immunoglobulin-beta CAR T Cells

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of T-lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR) targeting immunoglobulin-beta (Igb), with potential immunostimulating and antineoplastic activities. Upon administration, the anti-Igb CAR T cells are directed to, specifically bind to, and induce selective toxicity in Igb antigen-expressing tumor cells.

**Synonyms:** - Anti-CD79b CAR T Cells - iCas9 CD79b-CAR T Cells