Thyroblastoma

**Semantic type:** Neoplastic Process

**Definition:** A high-grade, rapidly growing malignant embryonal neoplasm that arises from the thyroid gland. It is characterized by the presence of primitive follicular-like structures surrounded by primitive small cells and primitive spindle cell mesenchymal stroma. It is associated with DICER1 gene mutations. The prognosis is poor.

**Synonyms:** - Thyroid Gland Carcinosarcoma - Thyroid Gland Immature Teratoma - Thyroid Gland Malignant Teratoid Tumor - Thyroid Gland Malignant Teratoma - Thyroid Gland Teratocarcinosarcoma