HCFC1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HCFC1 wild-type allele is located in the vicinity of Xq28 and is approximately 25 kb in length. This allele, which encodes host cell factor 1 protein, plays a role in histone modification, transcriptional regulation, and herpes simplex virus gene transcription. Mutation of the gene is associated with cblX type methylmalonic aciduria and homocysteineima and X-linked mental redardation 3.

**Synonyms:** - CFF - HCF - HCF-1 - HCF1 - HFC1 - Host Cell Factor C1 (VP16-Accessory Protein) Gene - Host Cell Factor C1 wt Allele - MAHCX - MGC70925 - MRX3 - Mental Retardation, X-Linked 3 Gene - PPP1R89 - Protein Phosphatase 1, Regulatory Subunit 89 Gene - VCAF - VP16-Accessory Protein Gene - XLID3